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Riluzole


Riluzole Oral tablet

What is this medicine?

RILUZOLE (RIL yoo zole) slows down the progression of amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease

  • liver disease

  • an unusual or allergic reaction to riluzole, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after meals. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • allopurinol

  • amitriptyline

  • barbiturate, like phenobarbital

  • caffeine

  • carbamazepine

  • certain antibiotics called quinolones

  • methyldopa

  • omeprazole

  • phenacetin

  • rifampin

  • sulfasalazine

  • tacrine

  • theophylline

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Contact your doctor or health care professional if your symptoms get worse or if you have a fever, chills, or other signs of infection.

Avoid alcohol and tobacco smoking while you are taking this medicine. Alcohol can increase the risk of liver damage. Tobacco smoking can decrease the effect of this medicine. Ask your doctor or health care professional for ways to help you stop smoking or drinking.

You may get dizzy or lose your balance. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • fever, chills or infection

  • increased blood pressure

  • tingling, pricking, or burning sensation around the mouth

  • yellowing of the skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough

  • diarrhea

  • loss of appetite

  • nausea, vomiting

  • stomach pain

  • weak or tired

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.