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Thiethylperazine


Thiethylperazine injection

What is thiethylperazine injection?

THIETHYLPERAZINE (Norzine®, Torecan®) helps to control nausea and vomiting, including nausea that occurs after surgery, or with the treatment of cancer (chemotherapy). Generic thiethylperazine injections are not yet available.

NOTE: This drug is discontinued in the US.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood disorders or disease

  • difficutly passing urine

  • glaucoma

  • liver disease or jaundice

  • low blood pressure

  • Parkinson's disease or uncontrollable movement disorder

  • pheochromocytoma

  • prostate trouble

  • seizures (convulsions)

  • an unusual or allergic reaction to thiethylperazine, sulfites, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Thiethylperazine is for injection into a muscle. It is given by a health-care professional in a hospital or clinic setting.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What drug(s) may interact with thiethylperazine?

  • alcohol

  • bromocriptine

  • lithium

  • medicines for movement abnormalities as in Parkinson's disease, or for gastrointestinal problems

  • medicines for pain

  • seizure (convulsion) or epilepsy medicine

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking thiethylperazine?

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how thiethylperazine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.

Thiethylperazine can reduce the response of your body to heat or cold. Try not to get overheated. Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather.

Thiethylperazine can make your skin more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps or sun tanning beds or booths. Wear sunglasses to protect your eyes.

Your mouth may get dry, chewing sugarless gum or sucking hard candy and drinking plenty of water will help.

Try not to get any thiethylperazine injection solution on your skin; this can cause a skin rash. If you do get any on the skin, rinse off with plenty of cool water.

What side effects may I notice from receiving thiethylperazine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blurred vision

  • breast enlargement in men or women

  • breast milk in women who are not breast-feeding

  • chest pain, fast or irregular heartbeat

  • confusion, restlessness

  • difficulty breathing or swallowing

  • dizziness or fainting spells

  • drooling, shaking, movement difficulty (shuffling walk) or rigidity

  • fever, chills, sore throat

  • involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs

  • menstrual changes

  • seizures (convulsions)

  • sexual difficulties (decreased sexual desire or impotence)

  • slurred speech

  • stomach area pain

  • sweating

  • unusual weakness or tiredness

  • unusual bleeding or bruising

  • yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • constipation

  • difficulty passing urine

  • drowsiness

  • dry mouth

  • headache

  • increased sensitivity to the sun or ultraviolet light

  • skin rash, or itching

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F); do not freeze. Protect from light. Do not use if solution is discolored or there is a precipitate. Throw away any unused medicine after the expiration date.

Thiethylperazine suppositories

What are thiethylperazine suppositories?

THIETHYLPERAZINE (Norzine®, Torecan®) helps to control nausea and vomiting, including nausea that occurs after surgery, or with the treatment of cancer (chemotherapy). Generic thiethylperazine suppositories are not yet available.

NOTE: This drug is discontinued in the US.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood disorders or disease

  • difficutly passing urine

  • glaucoma

  • liver disease or jaundice

  • low blood pressure

  • Parkinson's disease or uncontrollable movement disorder

  • pheochromocytoma

  • prostate trouble

  • seizures (convulsions)

  • an unusual or allergic reaction to thiethylperazine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Thiethylperazine suppositories are put into the rectum (back passage). Do not take by mouth. Wash your hands. Take off the foil wrapping. Wet the tip of the suppository with water to make it easier to use. Lie on your side and raise your knee to your chest. Using your finger, gently push the suppository into the rectum. Hold it in place for a few minutes. Wash your hands. Use your doses at regular intervals. Do not use your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with thiethylperazine?

  • alcohol

  • bromocriptine

  • lithium

  • medicines for movement abnormalities as in Parkinson's disease, or for gastrointestinal problems

  • medicines for pain

  • seizure (convulsion) or epilepsy medicine

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking thiethylperazine?

Visit your prescriber or health care professional for regular checks on your progress. If you have been using thiethylperazine regularly, do not stop using it suddenly, this can cause nausea, vomiting, and dizziness. Ask your prescriber or health care professional for advice if you are to stop using this medicine.

If the suppository is too soft to use, hold it under cold running water or put in the refrigerator for 30 minutes before you remove the foil wrapping.

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how thiethylperazine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.

Thiethylperazine can reduce the response of your body to heat or cold. Try not to get overheated. Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather.

Thiethylperazine can make your skin more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps or sun tanning beds or booths. Wear sunglasses to protect your eyes.

Your mouth may get dry, chewing sugarless gum or sucking hard candy and drinking plenty of water will help.

Do not treat yourself for coughs, colds, sore throat, or allergies. Ask your prescriber or health care professional for advice.

If you are going to have surgery, tell your prescriber or health care professional that you are taking thiethylperazine.

What side effects may I notice from using thiethylperazine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blurred vision

  • breast enlargement in men or women

  • breast milk in women who are not breast-feeding

  • chest pain, fast or irregular heartbeat

  • confusion, restlessness

  • dark yellow or brown urine

  • difficulty breathing or swallowing

  • dizziness or fainting spells

  • drooling, shaking, movement difficulty (shuffling walk) or rigidity

  • fever, chills, sore throat

  • involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs

  • menstrual changes

  • seizures (convulsions)

  • sexual difficulties (decreased sexual desire or impotence)

  • slurred speech

  • stomach area pain

  • sweating

  • unusual weakness or tiredness

  • unusual bleeding or bruising

  • yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • constipation

  • difficulty passing urine

  • drowsiness

  • dry mouth

  • headache

  • increased sensitivity to the sun or ultraviolet light

  • skin rash, or itching

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature below 25 degrees C (77 degrees F); do not freeze. Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Thiethylperazine tablets

What are thiethylperazine tablets?

THIETHYLPERAZINE (Norzine®, Torecan®) helps to control nausea and vomiting, including nausea that occurs after surgery, or with the treatment of cancer (chemotherapy). Generic thiethylperazine tablets are not yet available.

NOTE: This drug is discontinued in the US.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood disorders or disease

  • difficutly passing urine

  • glaucoma

  • liver disease or jaundice

  • low blood pressure

  • Parkinson's disease or uncontrollable movement disorder

  • pheochromocytoma

  • prostate trouble

  • seizures (convulsions)

  • an unusual or allergic reaction to thiethylperazine, tartrazine dye, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I take this medicine?

Take thiethylperazine tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with thiethylperazine?

  • alcohol

  • bromocriptine

  • lithium

  • medicines for movement abnormalities as in Parkinson's disease, or for gastrointestinal problems

  • medicines for pain

  • seizure (convulsion) or epilepsy medicine

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking thiethylperazine?

Visit your prescriber or health care professional for regular checks on your progress. If you have been taking thiethylperazine regularly, do not stop taking it suddenly, this can cause nausea, vomiting, and dizziness. Ask your prescriber or health care professional for advice if you are to stop taking this medicine.

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how thiethylperazine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.

Thiethylperazine can reduce the response of your body to heat or cold. Try not to get overheated. Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather.

Thiethylperazine can make your skin more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps or sun tanning beds or booths. Wear sunglasses to protect your eyes.

Your mouth may get dry, chewing sugarless gum or sucking hard candy and drinking plenty of water will help.

Do not treat yourself for coughs, colds, sore throat, or allergies. Ask your prescriber or health care professional for advice.

If you are going to have surgery, tell your prescriber or health care professional that you are taking thiethylperazine.

What side effects may I notice from taking thiethylperazine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blurred vision

  • breast enlargement in men or women

  • breast milk in women who are not breast-feeding

  • chest pain, fast or irregular heartbeat

  • confusion, restlessness

  • dark yellow or brown urine

  • difficulty breathing or swallowing

  • dizziness or fainting spells

  • drooling, shaking, movement difficulty (shuffling walk) or rigidity

  • fever, chills, sore throat

  • involuntary or uncontrollable movements of the eyes, mouth, head, arms, and legs

  • menstrual changes

  • seizures (convulsions)

  • sexual difficulties (decreased sexual desire or impotence)

  • slurred speech

  • stomach area pain

  • sweating

  • unusual weakness or tiredness

  • unusual bleeding or bruising

  • yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • constipation

  • difficulty passing urine

  • drowsiness

  • dry mouth

  • headache

  • increased sensitivity to the sun or ultraviolet light

  • skin rash, or itching

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.