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Breast Cancer Overview


Breast Cancer Overview

The body is made up of various kinds of cells, which normally divide in an orderly way to produce more cells only when they are needed. Cancer is a group of diseases more than 100 types that occur when cells become abnormal and divide without control or order.

What is a tumor?

When cells divide when new cells are not needed, too much tissue is formed. This mass of extra tissue, called a tumor, can be benign or malignant.

  • Benign tumors:

    • Are not cancer

    • Can usually be removed

    • Are rarely a threat to life

    • Do not come back in most cases

    • Do not spread to other parts of the body and the cells do not invade other tissues

  • Malignant tumors:

    • Are cancer

    • May be a threat to life

    • Often can be removed, but sometimes grow back

    • Can invade and damage nearby tissues and organs

    • Metastasize. Cancer cells can break away from a malignant tumor and enter the bloodstream or lymphatic system to form tumors in other parts of the body.

What are the different types of breast cancer?

There are several types of breast cancer, including:

  • Ductal carcinoma. This is the most common type and it begins in the lining of the ducts.

  • Lobular carcinoma. This is another common type and it occurs in the lobules (milk-producing glands).

  • Paget disease. This is a rare form of breast cancer that begins in the glands in or under the skin. It is often characterized by inflamed, red patches on the skin. Because Paget disease often originates from breast duct cancer, the eczema-like cancer usually appears around the nipple.

  • Inflammatory breast cancer. This is a rare form of invasive breast cancer. Usually there is no lump or tumor; rather this cancer makes the skin of the breast look red and feel warm. The breast skin also looks thick and pitted, much like an orange peel.

  • Triple negative breast cancers. These are breast cancers (most often invasive ductal carcinomas) that do not have estrogen receptors and progesterone receptors, and do not have an excess of the HER2 protein on the cancer cell surfaces. These breast cancers tend to occur more often in younger women and in African-American women. They tend to grow and spread faster than most other types of breast cancer.

When breast cancer metastasizes, or spreads outside the breast, cancer cells are often found in the lymph nodes under the arm. If the cancer has reached these nodes, it may mean that cancer cells have spread to other parts of the body.

Cancer that spreads is the same disease and has the same name as the original, or primary cancer. When breast cancer spreads, it is called metastatic breast cancer, even though the secondary tumor is in another organ. This may also be called distant disease.

Types of breast cancer, in alphabetical order, are:

Adenocarcinoma (adenocystic carcinoma)

Angiocarcinoma

Angiosarcoma

Ductal carcinoma in situ (DCIS)

Infiltrating (or invasive) ductal carcinoma (IDC)

Infiltrating (or invasive) lobular carcinoma (ILC)

Inflammatory breast cancer

Lobular carcinoma in situ (LCIS) (also called lobular neoplasia)

Medullary carcinoma

Metaplastic carcinoma

Mixed tumors

Mucinous carcinoma

Paget disease of the nipple

Papillary carcinoma

Phyllodes tumor (also spelled phylloides)

Triple-negative breast cancer

Tubular carcinoma