Osteosarcoma Treatments

Specific treatment for osteosarcoma will be determined by your doctor based on:

  • Your age, overall health, and medical history

  • Extent of the disease

  • Your tolerance for specific medications, procedures, or therapies

  • Expectations for the course of the disease

  • Your opinion or preference

Treatment may include:

  • Surgery (for example, biopsy, resections, bone/skin grafts, limb salvage procedures, reconstructions)

  • Amputation

  • Chemotherapy

  • Radiation therapy

  • Resections of metastases (spreading of the tumor to other locations)

  • Rehabilitation, including physical and occupational therapy, and psychosocial adapting

  • Prosthesis fitting and training

  • Supportive care for the side effects of treatment

  • Antibiotics to prevent and treat infections

  • Continued follow-up care to determine response to treatment, detect recurrent disease, and manage the side effects of treatment

Many patients, particularly those with higher grade tumors, will receive a combination of treatments. 

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